eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| histiocytic sarcoma | ||||
| Disease ID | 1466 |
|---|---|
| Disease | histiocytic sarcoma |
| Definition | Malignant neoplasms composed of MACROPHAGES or DENDRITIC CELLS. Most histiocytic sarcomas present as localized tumor masses without a leukemic phase. Though the biological behavior of these neoplasms resemble lymphomas, their cell lineage is histiocytic not lymphoid. |
| Synonym | [m]true histiocytic lymphoma histiocytic lymphoma, true histiocytic lymphomas, true histiocytic sarcoma (clinical) histiocytic sarcoma (disorder) histiocytic sarcoma (morphologic abnormality) histiocytic sarcoma [disease/finding] histiocytic sarcomas histiocytoses, true malignant histiocytosis, true malignant lymphoma, true histiocytic lymphomas, true histiocytic malignant histiocytoses, true malignant histiocytosis, true sarcoma, histiocytic sarcoma, histiocytic, malignant sarcomas, histiocytic true histiocytic lymphoma true histiocytic lymphoma (clinical) true histiocytic lymphoma (disorder) true histiocytic lymphoma (morphologic abnormality) true histiocytic lymphoma -retired- true histiocytic lymphoma [obs] true histiocytic lymphomas true malignant histiocytoses true malignant histiocytosis |
| Orphanet | |
| ICD10 | |
| UMLS | C0334663 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:18) C0024299 | lymphomas | 2 C0023418 | leukemia | 1 C0041296 | tuberculosis | 1 C0043117 | idiopathic thrombocytopenia | 1 C0019204 | hepatocellular carcinoma | 1 C0007115 | thyroid ca | 1 C0549473 | thyroid carcinoma | 1 C0024299 | malignant lymphoma | 1 C0598894 | monocytic leukemia | 1 C0238463 | papillary thyroid carcinoma | 1 C0023449 | acute lymphoblastic leukemia | 1 C0023448 | lymphoblastic leukemia | 1 C1328840 | autoimmune lymphoproliferative syndrome | 1 C0040034 | thrombocytopenia | 1 C0023443 | hairy cell leukemia | 1 C0024299 | malignant lymphomas | 1 C0334634 | mantle cell lymphoma | 1 C0023465 | acute monocytic leukemia | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | (Waiting for update.) |
| Locus | (Waiting for update.) |
| Disease ID | 1466 |
|---|---|
| Disease | histiocytic sarcoma |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:11) HP:0002664 | Neoplasia | 5 HP:0006721 | Acute lymphocytic leukemia | 1 HP:0001402 | Hepatocellular carcinoma | 1 HP:0002895 | Papillary thyroid carcinoma | 1 HP:0002890 | Thyroid carcinoma | 1 HP:0004845 | Acute monoblastic leukemia | 1 HP:0001873 | Low platelet count | 1 HP:0030731 | Carcinoma | 1 HP:0001909 | Leukemia | 1 HP:0001973 | Autoimmune thrombocytopenia | 1 HP:0001289 | Confusion | 1 |
| Disease ID | 1466 |
|---|---|
| Disease | histiocytic sarcoma |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:1) C0149678 | epstein-barr virus infection |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
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| (Waiting for update.) | |
All Snps(Total Genotypes:1) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs113488022 | 24720374 | 673 | BRAF | umls:C0334663 | BeFree | BRAF(V600E) was not limited to LCH and was detected more frequently in histiocytic sarcoma. | 0.000271442 | 2014 | BRAF | 7 | 140753336 | A | T,G,C |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
| Disease ID | 1466 |
|---|---|
| Disease | histiocytic sarcoma |
| Case | (Waiting for update.) |